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Published on: November 14, 2025
Harnessing Piezoelectric Biomaterials for Pathogenic Eradication and Tissue Regeneration
Wenxuan Mao1, Xiaoye Li1, Ao He1
1Institute of Stomatology Nanjing Stomatological Hospital Affiliated Hospital of Medical School Nanjing University Nanjing China.
Piezoelectric biomaterials offer a novel solution for combating infections and promoting tissue healing by converting mechanical energy into therapeutic electrochemical energy. These advanced materials show promise in antibacterial treatments and regenerative medicine.
Area of Science:
- Biomaterials Science
- Catalysis
- Regenerative Medicine
Background:
- Rising infections and delayed wound healing necessitate advanced therapeutic strategies.
- Piezoelectric catalytic therapy offers a promising approach by converting mechanical to electrochemical energy.
- Conventional piezoelectric materials have limitations in biocompatibility and catalytic efficiency.
Purpose of the Study:
- To review recent progress in piezoelectric biomaterials for infection control and tissue regeneration.
- To explore classifications, mechanisms, and property enhancement of piezoelectric biomaterials.
- To identify challenges and future directions for clinical translation.
Main Methods:
- Systematic literature review of piezoelectric biomaterials.
- Analysis of piezoelectric catalysis mechanisms.
- Evaluation of material properties and enhancement techniques.
Main Results:
- Piezoelectric biomaterials demonstrate enhanced biocompatibility and piezoelectric performance.
- Applications in pathogenic eradication and tissue regeneration are expanding.
- Various methods exist to optimize material properties for improved efficacy.
Conclusions:
- Piezoelectric biomaterials are a promising platform for antibacterial and regenerative applications.
- Further research is needed for material optimization and clinical translation.
- This field holds significant potential for transformative biomedical innovations.
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