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Updated: Mar 12, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Topical treatments for chronic plaque psoriasis
Laurence Le Cleach1,2, Sivem Afach2, Areti Angeliki Veroniki3
1Department of Dermatology, Hôpital Henri Mondor, Créteil, France.
This review will compare topical treatments for plaque psoriasis. It aims to rank treatments by effectiveness and safety using network meta-analysis.
Area of Science:
- Dermatology
- Pharmacology
- Evidence Synthesis
Background:
- Plaque psoriasis is a chronic inflammatory skin condition.
- Topical treatments are a common therapeutic approach.
- A comprehensive comparison of current topical agents is needed.
Purpose of the Study:
- To evaluate the relative benefits and harms of topical pharmacological treatments for plaque psoriasis.
- To rank the effectiveness and safety of these treatments.
- To inform clinical decision-making through a network meta-analysis.
Main Methods:
- This is a protocol for a Cochrane Review (intervention).
- A network meta-analysis will be conducted.
- The review will synthesize evidence on topical pharmacological treatments for plaque psoriasis.
Main Results:
- Results are pending the completion of the review and meta-analysis.
Conclusions:
- Conclusions will be drawn upon the synthesis of evidence regarding the comparative effectiveness and safety of topical treatments for plaque psoriasis.
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