Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

What is Genetic Engineering?00:49

What is Genetic Engineering?

81.0K
Overview
81.0K
Plant Breeding and Biotechnology01:59

Plant Breeding and Biotechnology

22.1K
Crop cultivation has a long history in human civilization, with records showing the cultivation of cereal plants beginning at around 8000 BC. This early plant breeding was developed primarily to provide a steady supply of food.
22.1K
In-vitro Mutagenesis01:16

In-vitro Mutagenesis

17.5K
To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.
17.5K
CRISPR01:59

CRISPR

58.6K
Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced...
58.6K
Transgenic Organisms00:53

Transgenic Organisms

34.2K
Overview
34.2K
RNA Editing02:23

RNA Editing

10.1K
RNA editing is a post-transcriptional modification where a precursor mRNA (pre-mRNA) nucleotide sequence is changed by base insertion, deletion, or modification. The extent of RNA editing varies from a few hundred bases, in mitochondrial DNA of trypanosomes, to a just single base, in nuclear genes of mammals. Even a single base change in the pre-mRNA can convert a codon for one amino acid into the codon for another amino acid or a stop codon. This type of re-coding can significantly affect the...
10.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Perceptions and practices on substandard and falsified medicines in humans and animals in Wakiso district, Uganda: A qualitative study.

PloS one·2025
Same author

Evaluation of a targeted enrichment panel for gene editing detection and assessment of population variation in Thoroughbred horses.

Animal genetics·2025
Same author

Knowledge, attitudes and practices on substandard and falsified medicines for human and animal use in Wakiso district, Uganda.

Journal of pharmaceutical policy and practice·2025
Same author

Risk factors for fatality in jump racing Thoroughbreds in Great Britain (2010-2023).

Equine veterinary journal·2024
Same author

Analytical advances in horseracing medication and doping control from 2018 to 2023.

Drug testing and analysis·2024
Same author

Detection of transgenes in equine dried blood spots using digital PCR and qPCR for gene doping control.

Drug testing and analysis·2024

Related Experiment Video

Updated: Mar 13, 2026

Author Spotlight: Streamlining Rice Breeding with CRISPR/Cas for Obtaining Optimal Phenotypic and Agronomic Traits
09:43

Author Spotlight: Streamlining Rice Breeding with CRISPR/Cas for Obtaining Optimal Phenotypic and Agronomic Traits

Published on: January 3, 2025

3.6K

Gene Editing and the Future of Thoroughbred Breeding and Racing.

Edward Ryder1, James Given2, Natasha Hamilton3

  • 1LGC Ltd, Fordham, UK.

Drug Testing and Analysis
|March 11, 2026
PubMed
Summary

Prohibited gene editing in horses can lead to unintended genetic changes. Undetected alterations threaten horse welfare and breed integrity across generations.

Keywords:
gene dopinggene editinghorsehorseracingthoroughbred

More Related Videos

Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms
09:51

Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms

Published on: May 25, 2018

36.1K
Efficient Genome Editing of Mice by CRISPR Electroporation of Zygotes
07:17

Efficient Genome Editing of Mice by CRISPR Electroporation of Zygotes

Published on: December 16, 2022

4.3K

Related Experiment Videos

Last Updated: Mar 13, 2026

Author Spotlight: Streamlining Rice Breeding with CRISPR/Cas for Obtaining Optimal Phenotypic and Agronomic Traits
09:43

Author Spotlight: Streamlining Rice Breeding with CRISPR/Cas for Obtaining Optimal Phenotypic and Agronomic Traits

Published on: January 3, 2025

3.6K
Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms
09:51

Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms

Published on: May 25, 2018

36.1K
Efficient Genome Editing of Mice by CRISPR Electroporation of Zygotes
07:17

Efficient Genome Editing of Mice by CRISPR Electroporation of Zygotes

Published on: December 16, 2022

4.3K

Area of Science:

  • Equine genetics
  • Animal biotechnology
  • Bioethics

Background:

  • Gene editing technologies offer potential benefits but carry risks.
  • Prohibited genetic modification in horses is a growing concern.
  • The long-term consequences of undetected gene edits are unknown.

Purpose of the Study:

  • To examine the potential outcomes of prohibited gene editing in horses.
  • To assess the risks associated with undetected genetic alterations.
  • To highlight the implications for equine welfare and breed integrity.

Main Methods:

  • Review of current gene editing techniques and their application in equine reproduction.
  • Analysis of potential genetic and phenotypic consequences of edits.
  • Evaluation of detection methods for genetic modifications in horse populations.

Main Results:

  • Prohibited gene editing can result in both intended and unintended genetic modifications.
  • Undetected edits can become established in subsequent generations.
  • Significant threats to equine welfare and breed integrity are identified.

Conclusions:

  • Strict monitoring and regulation of gene editing in horses are crucial.
  • Developing reliable methods for detecting genetic alterations is essential.
  • Addressing the ethical and welfare implications of gene editing is paramount for preserving breed integrity.