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Published on: April 11, 2018
Successful Treatment of Cutaneous Squamous Cell Carcinoma Complicated by Myelodysplastic Syndrome Using Combined
Yunwei Yang1,2,3,4, Zhenlin Li1,2,3,4, Long Wen2,3,4
1School of Medicine Anhui University of Science and Technology Huainan China.
Abstract:
Cutaneous squamous cell carcinoma (cSCC) is the second most common type of non-melanoma skin cancer. When the cSCC patient is complicated by myelodysplastic syndromes (MDS), treatment becomes particularly challenging due to immunosuppression, bleeding risk, and poor tolerance to conventional therapies. Here, we report a case of a 77-year-old woman with cSCC and MDS who was successfully treated by a combination of narrow-margin surgical excision and 5-aminolevulinic acid photodynamic therapy (ALA-PDT). No recurrence was observed during a six-month follow-up. This approach may offer a valuable therapeutic option for similar high-risk cSCC patients.
