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Target Tissue Identification Based on Image Processing for Regulating Automatic Robotic Lung Biopsy Sampler: Onsite

Maria Monserrat Diaz-Hernandez1, Gerardo Ramirez-Nava2, Isaac Chairez2

  • 1Tecnologico de Monterrey, School of Engineering and Sciences, Guadalajara 45210, Mexico.

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|March 14, 2026
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Summary
This summary is machine-generated.

This study introduces an autonomous robotic system for lung biopsies, using image processing and a closed-loop controller to precisely target and sample simulated cancerous tissue with high accuracy.

Keywords:
automatic biopsy samplingimage processingmedical robotsmultiple robot configurationsradio-pharmaceutical

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Area of Science:

  • Robotics
  • Medical Imaging
  • Oncology

Background:

  • Cancer diagnosis relies heavily on biopsies, but manual procedures face challenges like tissue movement and targeting accuracy, especially in lung biopsies.
  • Robotic assistance offers potential solutions to enhance precision and automation in biopsy procedures.

Purpose of the Study:

  • To design and implement an autonomous image processing algorithm within a closed-loop controller for a robotic manipulator to perform emulated lung biopsies.
  • To accurately identify cancerous tissue, determine target trajectories, and guide a robotic biopsy needle.

Main Methods:

  • Development of a six-degree-of-freedom robotic manipulator integrated with an image processing algorithm for autonomous operation.
  • Utilized a realistic lung motion emulator with a photon emitter to simulate radiopharmaceutical identification of cancerous tissue.
  • Implemented a finite-time convergent controller to guide the robotic manipulator's end effector to the tumor's centroid within a defined time.

Main Results:

  • The image processing algorithm successfully identified the centroid and boundaries of simulated cancerous tissue.
  • The robotic system achieved precise tracking of the emulated tumor with a deviation of 0.52 mm.
  • The controller demonstrated effective guidance, with a settling time of less than 1 second for trajectory tracking.

Conclusions:

  • The autonomous robotic system with image processing and a finite-time convergent controller shows significant promise for accurate and efficient lung biopsies.
  • This technology can potentially overcome manual biopsy limitations, improving diagnostic procedures for lung cancer.