Significant Improvement in High Myopic Anisometropic Amblyopia Treated With Repeated Low-Level Red-Light (RLRL)...

Area of Science:

• Ophthalmology
• Pediatric Ophthalmology
• Myopia Research

Background:

• High myopic anisometropic amblyopia presents a significant challenge for traditional treatments.
• Existing interventions like spectacles, occlusion, and atropine have limited success in correcting refractive imbalance and controlling myopia progression.

Purpose of the Study:

• To investigate the efficacy of repeated low-level red-light therapy (RLRLT) in managing high myopic anisometropic amblyopia.
• To assess RLRLT's impact on both visual acuity and refractive error in a pediatric case.

Main Methods:

• A case report involving a 5-year-old male diagnosed with high myopic anisometropic amblyopia.
• Treatment involved full correction spectacles combined with RLRLT over a 3-year follow-up period.
• Refractive error, best-corrected visual acuity (BCVA), and axial length were monitored.

Main Results:

• The highly myopic eye showed significant improvement: refractive error shifted from -7.75 D to -4.75 D, and BCVA recovered to 20/20.
• Axial length in the affected eye reduced by 1.01 mm (from 27.79 mm to 26.78 mm).
• The fellow eye remained relatively stable.

Conclusions:

• Repeated low-level red-light therapy demonstrated potential in simultaneously normalizing visual acuity and reducing axial length in high myopic anisometropic amblyopia.
• This case suggests RLRLT as a potential novel therapeutic option, warranting further investigation.
• Larger controlled trials are necessary to confirm efficacy and understand underlying mechanisms before clinical adoption.