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Related Concept Videos

Infertility in Females01:28

Infertility in Females

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Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
Endometriosis, a condition characterized by abnormal growth of...
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Infertility in Males01:23

Infertility in Males

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Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
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CRISPR01:59

CRISPR

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Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced...
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Disorders of the Female Reproductive System01:24

Disorders of the Female Reproductive System

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The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
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Overview of the Reproductive System01:31

Overview of the Reproductive System

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The reproductive system generates offspring, ensuring the survival of the species. In humans, the reproductive system is complex and involves a variety of organs and hormones that work together to ensure successful reproduction.
The gonads, or primary reproductive organs, produce gametes and sex hormones. In males, the testes produce spermatozoa and testosterone, which is responsible for developing secondary male sex characteristics, including a deeper voice, larger muscles, facial and body...
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Single Nucleotide Polymorphisms-SNPs01:05

Single Nucleotide Polymorphisms-SNPs

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A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
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Updated: Mar 17, 2026

COVID-19 Seroprevalence Test for IgG Antibody Levels Among Healthy Donors Across Different Pandemic Phases in Jeddah
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SARS-CoV-2 Associated Impact on Reproductive Health: A Global Perspective.

Priya Kalsi1, Navita Aggarwal2, Kamla Kant Shukla3

  • 1Department of Biochemistry, All India Institute of Medical Sciences, Bathinda, Punjab 151001 India.

Indian Journal of Clinical Biochemistry : IJCB
|March 16, 2026
PubMed
Summary

The COVID-19 pandemic negatively impacted reproductive health in both men and women, affecting fertility treatments. SARS-CoV-2 poses risks to long-term reproductive function, necessitating further research.

Keywords:
Assisted reproductive technologyInfertilityReproductive healthSARS-CoV-2

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Area of Science:

  • Reproductive Endocrinology
  • Virology
  • Public Health

Background:

  • The SARS-CoV-2 pandemic caused widespread health concerns and disrupted medical services.
  • While no longer a global emergency, potential long-term reproductive health risks persist.
  • Pandemic-related restrictions impacted fertility treatments and patient care.

Purpose of the Study:

  • To examine the effects of SARS-CoV-2 on male and female reproductive health.
  • To discuss the challenges faced by assisted reproductive technology (ART) during the pandemic.
  • To highlight the ongoing concerns regarding reproductive health post-pandemic.

Main Methods:

  • Review of existing literature on SARS-CoV-2 and reproductive health.
  • Analysis of reported changes in menstrual cycles and sexual function in females.
  • Examination of the impact of ACE2 expression on male reproductive function.

Main Results:

  • Females experienced menstrual irregularities, thyroid dysfunction, and stress-related sexual issues.
  • Male reproductive organs were also affected, with ACE2 expression linked to functional alterations.
  • Disruptions in ART services posed significant challenges for infertile couples.

Conclusions:

  • SARS-CoV-2 significantly impacts both female and male reproductive health.
  • The pandemic created substantial obstacles for individuals undergoing fertility treatments.
  • Continued monitoring and research are crucial for understanding and addressing long-term reproductive health consequences.