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The Biophysics of Radiofrequency Ablation and Factors Affecting Lesion Size
Alexander P Bates1, Waqas Ullah1,2
1Cardiology Department, University Hospital Southampton Southampton, UK.
Abstract:
Radiofrequency ablation is the mainstay of interventional electrophysiology. The biophysics of radiofrequency ablation involve converting electrical energy into heat to irreversibly damage an area of myocardium. To create an ablation lesion, a temperature of >50°C must be generated in the tissue for 60 seconds. This is influenced by factors affecting either the current delivered, electrode impedance, ablation duration or the thermoconductive properties of the tissue. These factors can be altered to affect ablation lesion size to optimise arrhythmia treatment.
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