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Detecting chromatin state alterations in PBMCs associated with Type 2 Diabetes Mellitus

Maryam Moazeni Afarani1, Rajshikhar Gupta1,2,3, Caroline Uhler4,3

  • 1Laboratory of Multiscale Bioimaging, Paul Scherrer Institut, Villigen, Aargau, Switzerland.

Communications Medicine
|March 18, 2026
PubMed
Summary

A new chromatin imaging assay offers a cost-effective way to monitor Type 2 Diabetes Mellitus (T2DM) by analyzing immune cell changes. This method identifies distinct peripheral blood mononuclear cell (PBMC) patterns linked to T2DM progression.

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