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Large field-of-view ptychographic imaging with a large probe and an iterative partition reconstruction method.
Optics Express
|March 18, 2026
Summary
This study introduces a new X-ray ptychography method combining large-probe scanning with iterative partition reconstruction. This approach significantly enhances efficiency for large field-of-view imaging, overcoming current time and data challenges.
Area of Science:
- Materials Science
- Nanotechnology
- X-ray Imaging
Background:
- X-ray ptychography offers nanoscale resolution and large fields-of-view (FOV).
- Current limitations include high time costs and reconstruction complexity for large FOV datasets.
- Challenges arise from large data volumes and probe variations.
Purpose of the Study:
- To develop a synergistic method for improving the efficiency of large FOV X-ray ptychography.
- To address the time cost and reconstruction difficulties associated with large FOV ptychography.
- To provide a new solution for high-resolution, large FOV ptychography.
Main Methods:
- Integration of a large-probe, large-step scanning strategy.
- Development of an upsampling-multimode fusion algorithm for probe size extension.
- Implementation of an iterative partition reconstruction (IPR) algorithm with adaptive sample splicing.
Main Results:
- Acquisition efficiency improved over 12 times compared to conventional methods.
- Reduced hardware requirements and improved reconstruction efficiency.
- Suppressed artifacts due to probe variations and eliminated overlapping redundancy.
Conclusions:
- The developed strategy offers a new solution for high-resolution, large FOV ptychography.
- The synergistic method effectively overcomes limitations of current X-ray ptychography techniques.
- Demonstrated performance with experimental verification using large probes.

