Related Experiment Video
Updated: Mar 19, 2026
11:22
Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
Published on: October 15, 2019
31.5K
Genomic Extension of HLA-C*03:31, by Next-Generation Sequencing
Jarret Merschman1, Derek Benidt1, Justin Kreuter1
1Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
HLA
|March 18, 2026
Abstract
None:
The HLA-C*03:31 allele is characterised by a nucleotide substitution at genomic DNA position 400 in exon 2.
Related Concept Videos
01:11Genome-wide Association Studies-GWAS
16.5K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
GWAS does not require the identification of the target gene involved in...
16.5K
03:00Next-generation Sequencing
100.7K
The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features....
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features....
100.7K