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Long-term Potentiation

Long-term Potentiation

Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre- and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.

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Related Experiment Video

Updated: Mar 24, 2026

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

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Published on: July 19, 2019

Chronic Active Lesions in Pediatric Multiple Sclerosis

Monica Margoni^1,2,3, Maria A Rocca^1,2,4, Massimo Filippi^1,2,3,4,5

¹Neuroimaging Research Unit, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy.

|March 23, 2026

Summary

No abstract available in PubMed .

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