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Updated: Mar 25, 2026

Isolating Free Carbenes, their Mixed Dimers and Organic Radicals
Published on: April 19, 2019
Iodosobenzene-Mediated Synthesis of 1-Benzothiazolyl-o-Carboranes
Huijin Guo1, Ji Wu1, Ke Cao2
1School of Materials Science and Engineering, Sichuan University of Science & Engineering, Zigong 643000, P. R. China.
None:
The innovation of synthetic strategies for incorporating heterocycles into carborane is a significant objective in the realm of carborane chemistry on account of the fact that heterocyclic skeletons are widespread among natural products as well as bioactive molecules and the versatility applications of carboranes in medicinal chemistry and materials science. This method disclosed a facile and practical protocol for the synthesis of 1-benzothiazolyl-o-carboranes through an iodosobenzene-mediated intramolecular oxidative annulation process of C(1)-N-arylthioaacylamino-o-carborane. A series of 1-benzothiazolyl-o-carboranes have been synthesized in good to excellent yields. This work would be an important reference for the synthesis of aromatic heterocycle-carborane derivatives and promote their applications in designing drug candidates and functional materials.
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