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Comparison of endoscopy and mobile health index for ulcerative colitis
Frigg Åslagusdatter Sommervoll1, Martha Maria Eide Songstad1, Hilde Løland von Volkmann2
1Institute of Clinical Medicine, University of Bergen, Bergen, Norway.
Background And Aims:
At Haukeland University Hospital, the Mobile Health Index for Ulcerative Colitis (MHI-UC), a patient-reported outcome measure (PROM), is used in the outpatient clinic to detect disease activity in patients. The primary objective of the study was to compare the MHI-UC with the endoscopic Mayo score (e-MAYO) in a Norwegian cohort, and to investigate the impact on treatment decisions and response.
Materials And Methods:
The study is single-center and retrospective. Patients were identified by searching patient journals and screened for participation. Patients who had answered the MHI-UC within ±4 weeks of endoscopy, with no change in treatment, were eligible. Clinical intervention involved treatment changes or referrals to endoscopy or cross-sectional imaging. For those with multiple endoscopies, data from all were collected. Response was defined as a change in e-MAYO score of 1 or more.
Results:
The MHI-UC correlated with endoscopic activity scored by e-MAYO (r = 0.64, p < 0.001). The AUROC for detecting endoscopic disease activity was 0.92 for e-MAYO > 1 and 0.78 for e-MAYO > 0. Patients receiving a clinical intervention (4.3 ± 3.5 vs 2.3 ± 2.7, p = 0.001) or with a change in e-MAYO (3.9 ± 2.7 points vs 0.7 ± 2.8 points) had a significantly higher MHI-UC compared to those without need for intervention.
Conclusions:
The MHI-UC corresponds well with the endoscopic evaluation in patients with UC. The MHI-UC can be used to detect moderate to severe disease activity in UC with high accuracy and to detect changes in endoscopic activity.
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