Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Acne Infection

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Integrating Technology into Urticaria Management: Telemedicine, Remote Monitoring and Patient-Centered Care.

Biomedicines·2026

Same author

Sex Differences in Oxidative Stress Concerning Allergic Diseases.

Biomolecules·2025

Same author

Effectiveness and Safety of Ruxolitinib Cream 15 mg/g in Patients With Non-Segmental Vitiligo: A Real-Life Study.

International journal of dermatology·2025

Same author

Successful Treatment of Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) With Tezepelumab: A Case Report.

Immunology·2025

Search research articles

Related Experiment Video

Updated: Mar 28, 2026

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients

Published on: March 1, 2024

Steroid-Modified Scabies: Quantifying a Clinically Recognized but Understudied Problem.

Attilio Di Girolamo¹, Mattia Cristallo²

¹Department of Precision and Regenerative Medicine and Ionian Area, Regional Reference Center for Allergic and Immunological Diseases, Bari, Italy.

International Journal of Dermatology

|March 26, 2026

Summary

Topical corticosteroid use in undiagnosed itchy skin conditions can worsen scabies. Steroid exposure is linked to increased mite load, wider rash, and slower recovery compared to standard scabies treatments.

Keywords:

corticosteroid exposure scabies severity scale steroid‐modified scabies

More Related Videos

SCAnED - An Open-source Skin Segmentation Macro for Semi-automated Cell and Nuclei Detection in Epidermal and Dermal Skin Compartments

SCAnED - An Open-source Skin Segmentation Macro for Semi-automated Cell and Nuclei Detection in Epidermal and Dermal Skin Compartments

Published on: August 8, 2025

Related Experiment Videos

Last Updated: Mar 28, 2026

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients

Published on: March 1, 2024

SCAnED - An Open-source Skin Segmentation Macro for Semi-automated Cell and Nuclei Detection in Epidermal and Dermal Skin Compartments

SCAnED - An Open-source Skin Segmentation Macro for Semi-automated Cell and Nuclei Detection in Epidermal and Dermal Skin Compartments

Published on: August 8, 2025

Area of Science:

Dermatology
Parasitology
Pharmacology

Background:

Pruritic dermatoses are common skin conditions causing itching.
Scabies is a contagious parasitic infestation.
Corticosteroids are frequently used to manage inflammatory skin conditions.

Purpose of the Study:

To investigate the impact of corticosteroid use on the clinical presentation and progression of scabies.
To compare outcomes of scabies in patients exposed to corticosteroids versus those receiving standard antiparasitic therapy.

Main Methods:

Retrospective analysis of patient cases with undiagnosed pruritic dermatoses.
Comparison of clinical parameters including mite burden, disease extent, and healing time.
Evaluation of diagnostic delays and treatment efficacy.

Main Results:

Corticosteroid exposure in undiagnosed scabies was associated with a higher mite burden.
Patients using steroids showed greater disease extent and delayed healing.
Prolonged steroid use masked inflammation, delaying scabies diagnosis and facilitating parasite persistence.

Conclusions:

Corticosteroid use can significantly alter the clinical course of scabies, potentially worsening the infestation.
Delayed diagnosis and treatment of scabies can occur due to masked inflammation from steroid use.
Standard antiparasitic therapy is more effective than corticosteroid use for managing scabies.