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Dietary Supplements in Public Health: Benefits, Risks, and Emerging Gel/Hydrogel Delivery Systems
Anca Daniela Raiciu1,2,3, Georgeta Alexandru3, Cristina-Mihaela Luntraru3
1Department of Pharmacognosy, Phytochemistry, and Phytotherapy, Faculty of Pharmacy, Titu Maiorescu University, Gh. Şincai Street No. 16, District 4, 040314 Bucharest, Romania.
Dietary supplements offer benefits like improved well-being but pose risks such as toxicity and drug interactions. This review analyzes their pros and cons, especially for military populations, recommending evidence-based use.
Area of Science:
- Nutritional Science
- Pharmacology
- Public Health
Background:
- Global surge in dietary supplement use for health and disease prevention.
- Supplements present both advantages (micronutrient support, performance enhancement) and risks (toxicity, drug interactions, lack of validation).
- Need for nuanced analysis, especially in general and military populations.
Purpose of the Study:
- To conduct a nuanced analysis of the scientific literature on dietary supplements.
- To evaluate the advantages and drawbacks of supplement use.
- To provide recommendations for evidence-based use in civilian and military contexts.
Main Methods:
- Comprehensive review of peer-reviewed studies.
- Analysis of regulatory documents and expert guidelines.
- Inclusion of emerging delivery systems like nutritional gels and hydrogels.
Main Results:
- Identified key benefits including addressing deficiencies and enhancing performance.
- Highlighted significant risks such as toxicity and potential drug interactions.
- Examined novel delivery systems for improved bioavailability and tolerability.
Conclusions:
- Dietary supplements require careful consideration due to their dual nature of benefits and risks.
- Evidence-based recommendations are crucial for safe and effective supplement utilization.
- Advanced technologies like hydrogels signal a move towards precision nutrition.
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