Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Endoscopic Procedures III: Video Capsule Endoscopy01:28

Endoscopic Procedures III: Video Capsule Endoscopy

1.2K
Capsule endoscopy, or wireless or video capsule endoscopy, is a diagnostic procedure for examining the entire gastrointestinal tract. Patients swallow a capsule about the size of a vitamin tablet. The capsule is equipped with a transmitter, a battery, an LED light source, and a color video camera to capture images throughout the gastrointestinal tract. This procedure is particularly useful for diagnosing conditions such as Crohn's disease, ulcerative colitis, tumors, polyps, ulcers,...
1.2K
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy01:26

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

1.0K
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
1.0K
Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques01:30

Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques

814
Airway management is essential in emergency and surgical medicine, ensuring ventilation and oxygenation in patients who cannot maintain their own airway. Clinicians use a range of techniques and devices to secure the airway, depending on the patient’s condition and the clinical context. Key methods include endotracheal intubation, rapid sequence intubation (RSI), supraglottic airway devices, and advanced visualization aids. In cases where these approaches fail, surgical airway...
814

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pancrelipase Improves Symptoms of Exocrine Pancreatic Insufficiency and Health-Related Quality of Life in a Real-World Population of Patients with Chronic Pancreatitis.

Digestive diseases and sciences·2026
Same author

Esophageal myotomy and risk of esophageal cancer and mortality in achalasia: Real-world cohort study.

Endoscopy international open·2026
Same author

Toward the smart endoscopy center: evaluating the role of robots in the endoscopy unit.

Gastrointestinal endoscopy·2026
Same author

Comparison of antimigration versus conventional fully covered self-expandable metal stents for malignant distal biliary obstruction: a single-center long-term study.

Gastrointestinal endoscopy·2026
Same author

Cholangioscopic biopsy sample detection of bile duct invasion by hepatocellular carcinoma: an underappreciated entity.

iGIE : innovation, investigation and insights·2026
Same author

Diagnostic yield of endoscopic ultrasound-guided fine-needle biopsy of solid pancreatic lesions with tissue sent directly in formalin for histopathologic evaluation compared with cytology: a multicenter prospective pilot study.

Gastrointestinal endoscopy·2025
Same journal

Transform-The Path Forward: Endoscopy and the Science of Expertise.

Gastrointestinal endoscopy clinics of North America·2026
Same journal

Ushering in a New Era of Training in Endoscopy.

Gastrointestinal endoscopy clinics of North America·2026
Same journal

Where Do We Go from Here: Transforming Teaching Endoscopy Knowledge Using the Expert Performance Approach.

Gastrointestinal endoscopy clinics of North America·2026
Same journal

Integrating Artificial Intelligence into Endoscopy Training.

Gastrointestinal endoscopy clinics of North America·2026
Same journal

From Expert to Educator: Translating Expert Performance into Teachable Competencies Through Trainer Development in Endoscopic Simulation.

Gastrointestinal endoscopy clinics of North America·2026
Same journal

Implementing Endoscopy Simulation Nationally.

Gastrointestinal endoscopy clinics of North America·2026
See all related articles

Related Experiment Video

Updated: Mar 31, 2026

Endoscopic Vacuum Therapy for the Treatment of Anastomotic Leakage after Total Gastrectomy with Esophagojejunostomy
04:05

Endoscopic Vacuum Therapy for the Treatment of Anastomotic Leakage after Total Gastrectomy with Esophagojejunostomy

Published on: August 22, 2025

1.1K

Endoscopic Closure Techniques in Third-space Endoscopy.

Tara Keihanian1, Mohamed O Othman1

  • 1Division of Gastroenterology, Department of Medicine, Baylor College of Medicine, 7200 Cambridge Street, Suite 8B, Houston, TX 77030, USA.

Gastrointestinal Endoscopy Clinics of North America
|March 29, 2026
PubMed
Summary
This summary is machine-generated.

Closing mucosal incisions after third-space endoscopy is crucial but lacks a standard method. This review compares through-the-scope clips, over-the-scope clips, and endoscopic suturing for optimal closure in these advanced endoscopic procedures.

Keywords:
Endoscopic clipsEndoscopic closureEndoscopic suturePeroral endoscopic myotomyThird-space endoscopyTissue approximation device

More Related Videos

A Case Series of Successful Abdominal Closure Utilizing a Novel Technique Combining a Mechanical Closure System with a Biologic Xenograft that Accelerates Wound Healing
20:33

A Case Series of Successful Abdominal Closure Utilizing a Novel Technique Combining a Mechanical Closure System with a Biologic Xenograft that Accelerates Wound Healing

Published on: July 4, 2019

52.3K
An Ivor Lewis Esophagectomy Designed to Minimize Anastomotic Complications and Optimize Conduit Function
09:40

An Ivor Lewis Esophagectomy Designed to Minimize Anastomotic Complications and Optimize Conduit Function

Published on: April 17, 2020

15.5K

Related Experiment Videos

Last Updated: Mar 31, 2026

Endoscopic Vacuum Therapy for the Treatment of Anastomotic Leakage after Total Gastrectomy with Esophagojejunostomy
04:05

Endoscopic Vacuum Therapy for the Treatment of Anastomotic Leakage after Total Gastrectomy with Esophagojejunostomy

Published on: August 22, 2025

1.1K
A Case Series of Successful Abdominal Closure Utilizing a Novel Technique Combining a Mechanical Closure System with a Biologic Xenograft that Accelerates Wound Healing
20:33

A Case Series of Successful Abdominal Closure Utilizing a Novel Technique Combining a Mechanical Closure System with a Biologic Xenograft that Accelerates Wound Healing

Published on: July 4, 2019

52.3K
An Ivor Lewis Esophagectomy Designed to Minimize Anastomotic Complications and Optimize Conduit Function
09:40

An Ivor Lewis Esophagectomy Designed to Minimize Anastomotic Complications and Optimize Conduit Function

Published on: April 17, 2020

15.5K

Area of Science:

  • Gastroenterology
  • Endoscopic Surgery
  • Surgical Innovation

Background:

  • Third-space endoscopy, including peroral endoscopic myotomy (POEM), is increasingly used for esophageal and gastric motility disorders.
  • Effective closure of mucosal defects after third-space endoscopy is essential for patient outcomes.
  • Optimal endoscopic closure techniques remain debated, lacking a definitive consensus.

Purpose of the Study:

  • To compare different endoscopic closure techniques for mucosal incision sites in third-space endoscopy.
  • To evaluate the efficacy and safety of various closure methods.
  • To provide insights into selecting the best closure strategy for specific clinical scenarios.

Main Methods:

  • Review and comparison of available literature on endoscopic closure techniques.
  • Analysis of through-the-scope (TTS) clips, over-the-scope (OTS) clips, and endoscopic suturing (TTS and OTS).
  • Evaluation based on closure rates, adverse events, and procedural efficiency.

Main Results:

  • Each closure method (TTS clips, OTS clips, suturing) presents unique advantages and disadvantages.
  • Clip-based closures offer speed, while suturing may provide more robust closure.
  • The choice of method may depend on the size and location of the mucosal defect and operator experience.

Conclusions:

  • No single endoscopic closure technique is universally superior for all third-space endoscopic procedures.
  • Careful consideration of defect characteristics and available tools is necessary for optimal closure.
  • Further comparative studies are needed to establish evidence-based guidelines for mucosal closure in third-space endoscopy.