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An Intestinal Gut Organ Culture System for Analyzing Host-Microbiota Interactions
Published on: June 30, 2021
Impact of gut microbiota on human immune system development: A longitudinal study
Dipalben Shreyaskumar Patel1, Mukul Singh2, Vivekanand Ashok3
1Department of Obstetrics and Gynecology, Akshaydeep Hospital, Gujarat, India.
None:
The development of the immune system in early childhood is influenced by various factors, and the role of gut microbiota in this process remains a critical area of investigation. Therefore, it is of interest to investigate the impact of gut microbiota on immune system development in 110 children over three years. It found significant correlations between microbiota diversity and immune markers, with higher diversity linked to improved immune regulation. The study also highlighted the negative effects of early antibiotic use and the positive influence of a fiber-rich diet on gut microbiota composition and immune function. Thus, we show the critical role of early- life microbial exposures in shaping immune health.
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