Residual monomer release from different acrylic-based dental materials: An in vivo evaluation

Primary concern from residual monomer and other leachable components from denture base resins is allergic and sensitivity reactions among patients. Therefore, it is of interest to evaluate the leaching ability of residual methylmethacrylate monomer from heat polymerising acrylic, auto polymerising acrylic, auto polymerising acrylic cured under pot pressure, and thermoformed sheets in 40 children aged 7-14 years. Saliva samples were collected at 5 minutes, 1 hour, 24 hours, and 1 month after appliance insertion and analyzed by High Performance Liquid Chromatography. Results revealed significantly higher monomer release from auto polymerising acrylic materials, followed by heat cure, while thermoformed sheets showed no detectable release. The findings indicate thermoformed sheets are safer and more clinically acceptable alternatives for pediatric appliances.