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Application of Ultrasound and Shear Wave Elastography Imaging in a Rat Model of NAFLD/NASH
Published on: April 20, 2021
Assessment of chronic liver disease using shear wave elastography: Correlation with serum markers
Soumik Pal1, Rajeev Kumar Ranjan1, Suresh Kumar Toppo1
1Department of Radio-diagnosis, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India.
None:
Chronic liver disease requires accurate fibrosis assessment, with non-invasive tools gaining importance over biopsy. Hence, this cross- sectional study evaluated liver fibrosis in 122 CLD patients using shear wave elastography (SWE) and correlated findings with serum markers. SWE showed strong correlation with APRI (r=0.70) and platelet count (r=-0.70), and moderate correlations with AST and FIB-4. Optimal SWE cutoffs were 9.2 kPa for significant fibrosis and 15.38 kPa for cirrhosis, with excellent diagnostic accuracy (AUROC=0.99). SWE combined with serum markers-especially APRI-provides a reliable, non-invasive alternative for fibrosis assessment in CLD patients.
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