Case Report: Bilateral perineuroma of the orbit presenting as vertical binocular diplopia

In this case report, we describe a 65-year-old woman who presented to the ophthalmology clinic with vertical binocular diplopia for approximately 2 years. Visual exam was notable for bilateral proptosis and ophthalmoplegia. A computed tomography (CT) of the head revealed bilateral enhancing orbital masses. A biopsy was performed, and the result was positive for epithelial membrane antigen (EMA) and CD34, confirming a diagnosis of perineuroma. To our knowledge, this is the first reported case of bilateral perineuroma of the orbit, a rare location for an already uncommon benign tumor.