Related Experiment Video
Updated: Mar 31, 2026

Author Spotlight: Understanding Dynamic Cellular Behaviors in Adult Mouse Dental Tissue Renewal and Repairment
Published on: October 27, 2023
Resolving tooth development at single-cell resolution: advancing dental regeneration
Chengcheng Liao1,2,3, Jun Cai1,2, Yanmei Liu1,2
1Department of Orthodontics II, Affiliated Stomatological Hospital of Zunyi Medical University, Zunyi, China.
Abstract:
Tooth development is a continuous, highly orchestrated process that serves as an ideal model for dissecting the cellular and molecular mechanisms of organogenesis. In recent years, advances in single-cell transcriptomics have provided unprecedented insights into cellular heterogeneity, lineage trajectories, and molecular signaling networks during mouse and human tooth development, greatly enhancing our understanding of odontogenesis. Crucially, these single-cell-level studies of tooth development provide both a theoretical foundation and advanced strategies for dental tissue regeneration.

