Related Experiment Video
Updated: Jun 30, 2026

The Use of the Ex Vivo Chandler Loop Apparatus to Assess the Biocompatibility of Modified Polymeric Blood Conduits
Published on: August 20, 2014
Changes in Stimulant Use Over Time Among Men Who Have Sex with Men in Philadelphia, Baltimore, and Washington, DC,
Danielle German1, Tanner Nassau2, Karine Yenokyan3
1Department of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, Behavior and Society, 615 North Wolfe Street, Baltimore, MD, USA. danielle.german@jhu.edu.
Abstract:
Stimulant use among men who have sex with men (MSM) can contribute to HIV risk and care challenges. Monitoring and responding to local trends are critical for Ending the HIV Epidemic (EHE) initiatives. We assessed stimulant use patterns in Baltimore, Philadelphia, and Washington, DC from 2008 to 2023 using National HIV Behavioral Surveillance data. We collected cross-sectional data in each city using venue-based sampling in 2008, 2011, 2014, 2017, and 2023. We estimated average predicted probabilities of methamphetamine, powder cocaine, and crack cocaine use, and evaluated differences in prevalence of stimulant use overall and by race/ethnicity. In DC, stimulant use was stable or declined. Methamphetamine use remained stable overall (8%), with observed decreases among Hispanic MSM (13% to 4%). In Baltimore, methamphetamine use increased (2% to 5%) overall, while powder cocaine slightly declined overall (15% to 13%), with decreases among Black MSM but increases among White and Hispanic MSM. Crack cocaine decreased slightly (12% to 11%). In Philadelphia, methamphetamine use rose substantially (3% to 10%), with the largest increase among White MSM (3% to 19%). Powder cocaine use was highest in Philadelphia, reaching 41% among White MSM in 2023. Trends in stimulant use among MSM differed across these three EHE-funded cities. Philadelphia showed pronounced increases, particularly among White MSM, while DC and Baltimore exhibited more modest or stable patterns. Comparable local data sources are essential for identifying city- and subpopulation-specific trends to inform focused, equitable prevention strategies within EHE.
More Related Videos
Related Concept Videos
Longitudinal Research
Drugs Acting on Autonomic Ganglia: Stimulants
Ganglionic stimulants activate NM nicotinic receptors in autonomic ganglia, falling into two categories: nicotine mimetics [e.g., lobeline, dimethylpiperazine, tetramethylammonium] and muscarinic receptor agonists [e.g., muscarine, methacholine]. The first category's action is rapid and blocked by nicotinic receptor antagonists, while the second category's action is delayed and blocked by atropine-like agents. Nicotine, an alkaloid, affects the heart rate by stimulating sympathetic or...
Drug Abuse and Addiction: Pharmacological Phenomena
CNS Stimulants: Cocaine, Amphetamines and Cannabinoids
Stimulants
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
Amebiasis

