Related Experiment Video
Updated: Apr 8, 2026
09:59
An “All-laser” Endothelial Transplant
Published on: July 6, 2015
10.0K
Visual Outcomes and Safety of Ray-Tracing-Guided Laser-Assisted In Situ Keratomileusis: A Systematic Review and
Maximilian Friedrich1, Victor A Augustin1, Gerd U Auffarth1
1David J. Apple International Laboratory for Ocular Pathology and International Vision Correction Research Centre (IVCRC), Department of Ophthalmology, University of Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.
Ophthalmology and Therapy
|April 1, 2026
Summary
Ray-tracing-guided laser-assisted in situ keratomileusis (RTG-LASIK) is a safe and effective refractive surgery for myopia. This procedure significantly improves uncorrected and corrected distance visual acuity with a low complication rate.
Area of Science:
- Ophthalmology
- Refractive Surgery
- Corneal Surgery
Background:
- Ray-tracing-guided laser-assisted in situ keratomileusis (RTG-LASIK) utilizes objective measurements for myopia correction.
- This systematic review and meta-analysis was registered with PROSPERO (ID: CRD420251179631).
Purpose of the Study:
- To evaluate the visual outcomes and safety of RTG-LASIK for myopia with or without astigmatism.
- To synthesize current evidence on the efficacy of automated refractive surgery techniques.
Main Methods:
- Systematic literature review and meta-analysis of 14 clinical studies involving 1577 eyes.
- Searched Cochrane, Embase, PubMed, and Web of Science databases.
- Assessed risk of bias and synthesized data on visual acuity, refractive outcomes, and complications.
Main Results:
- 99.17% of eyes achieved 20/20 or better uncorrected distance visual acuity (UDVA).
- Only 2.21% of eyes lost one or more lines of corrected distance visual acuity (CDVA).
- Manifest refraction spherical equivalent was within 0.5 D of target in 95.21% of cases, with a slight trend toward overcorrection.
Conclusions:
- RTG-LASIK appears to be a safe and effective short-term procedure for improving vision in myopic eyes.
- Further prospective studies with longer follow-up are necessary to confirm long-term safety and efficacy.
