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Updated: Apr 3, 2026

High-throughput Screening for Chemical Modulators of Post-transcriptionally Regulated Genes
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Transcriptional Regulatory Modulation as a Potential Therapeutic Modality

Navneet Matharu1, Nadav Ahituv1

  • 1Department of Bioengineering and Therapeutic Sciences and Institute for Human Genetics, University of California, San Francisco, California, USA; email: nkmatharu@gmail.com, nadav.ahituv@ucsf.edu.

Annual Review of Genomics and Human Genetics
|April 1, 2026
PubMed
Summary

Gene expression modification systems offer therapeutic potential for diseases caused by altered gene levels. These programmable technologies are advancing toward clinical application, addressing delivery and other challenges.

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