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Updated: Apr 3, 2026
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A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
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Evolution of Clinical Indications for Mitral Valve Transcatheter Edge-to-Edge Repair
Carla Iglesias-Otero1,2, Julio Echarte-Morales1,2, David González-Fernández1,2
1Department of Cardiology, University Hospital Alvaro Cunqueiro, 36312 Vigo, Spain.
Reviews in Cardiovascular Medicine
|April 2, 2026
Summary
Mitral valve transcatheter edge-to-edge repair (M-TEER) is a safe and versatile treatment for severe mitral regurgitation (MR). This therapy is expanding to new patient groups and complex cases, offering improved outcomes.
Area of Science:
- Cardiology
- Interventional Cardiology
- Medical Devices
Background:
- Mitral regurgitation (MR) poses significant risks, especially in patients ineligible for surgery.
- Transcatheter edge-to-edge repair (M-TEER) has become a key intervention for severe MR.
- Guidelines now recommend M-TEER for secondary and selected primary MR cases.
Purpose of the Study:
- To review the expanding role and evolving indications of M-TEER.
- To highlight M-TEER's efficacy in complex cardiovascular scenarios.
- To discuss combined procedural strategies and future research directions.
Main Methods:
- Review of clinical trials and registries evaluating M-TEER.
- Analysis of M-TEER outcomes in diverse patient populations.
- Assessment of combined M-TEER strategies with other interventions.
Main Results:
- M-TEER demonstrates improved short-term outcomes compared to conservative therapy in acute MR post-myocardial infarction.
- The procedure is effective in complex cases like advanced heart failure, hypertrophic obstructive cardiomyopathy, and mitral annulus calcification.
- Combined M-TEER strategies and its use in moderate MR are emerging as viable options.
Conclusions:
- M-TEER is a safe and versatile therapy with a growing range of applications.
- Evidence supports its use across various clinical scenarios, including moderate MR.
- Further research is needed to confirm long-term outcomes and optimize patient selection.
Keywords:
acute mitral regurgitationexpanding indicationsheart failuremitral regurgitationmitral transcatheter edge-to-edge repairMore Related Videos
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