Related Experiment Video
Updated: Apr 3, 2026

MRI and PET in Mouse Models of Myocardial Infarction
Published on: December 19, 2013
Quantitative myocardial perfusion imaging across PET, SPECT, CMR, and CT
Yoko Kato1, Omar Chehab1, Bharath Ambale-Venkatesh2
1Division of Cardiology, Johns Hopkins University, Baltimore, MD, United States.
None:
Recent clinical trials demonstrating the prognostic value of coronary computed tomography angiography (CCTA), and the limited incremental prognostic benefit of ischemia-guided revascularization over optimal medical therapy, have shifted focus away from functional testing. Nevertheless, myocardial perfusion assessment remains essential in patients with known or suspected coronary artery disease (CAD), microvascular dysfunction, ischemia with normal coronary arteries (INOCA), coronary anomalies, and cardiomyopathies. Advances in positron emission tomography (PET), cardiovascular magnetic resonance (CMR), and computed tomography (CT) now enable absolute quantification of myocardial blood flow (MBF), providing improved diagnostic and prognostic performance and underscoring the need to reappraise myocardial perfusion imaging. This mini-review summarizes key physiological principles, contemporary acquisition and post-processing strategies, and the clinical relevance of myocardial perfusion imaging (MPI) across PET, Single Photon Emission Computed Tomography (SPECT), CMR, and CT, and discusses future perspectives in quantitative MPI.
More Related Videos
11:09High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals
Published on: December 16, 2022
08:13In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
Published on: February 16, 2016
Related Concept Videos
Imaging Studies for Cardiovascular System V: CT
Imaging Studies for Cardiovascular System IV: CMRI
Positron Emission Tomography
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...