The Role of Radiotherapy in the Management of Chest Wall Soft Tissue Sarcomas

Soft tissue sarcoma (STS) of the chest wall is a relatively uncommon presentation of STS, though a common subtype of truncal STS. Wide en-bloc resection is the foundation of multimodality treatment of STS, but surgical resection alone can produce suboptimal outcomes for many patients. In this article, we summarize existing literature on the role of radiotherapy in the management of chest wall STS and provide an overview of its recommended use with a focus on the ASTRO Guideline on Radiation Therapy for Treatment of Soft Tissue Sarcoma in Adults.