Related Experiment Video
Updated: Apr 5, 2026

Ex utero Electroporation and Whole Hemisphere Explants: A Simple Experimental Method for Studies of Early Cortical Development
Published on: April 3, 2013
Malformations of Cortical Development
Theodore Betting1, Theodore Passe1
1Department of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.
Abstract:
Malformations of cortical development are complex and diverse. They are an etiology for drug-resistant epilepsy, and their imaging presentation may be striking or quite subtle. There are multiple schemes to classify this pathology group. One of the most well known is to group disorders based on the type of embryologic error that leads to each malformation. They can also be grouped based on imaging appearance, with the morphology of the involved cerebral cortex acting as the first major distinction.
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