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Updated: Apr 5, 2026

Intestinal Stem Cell Isolation and Culture in a Porcine Model of Segmental Small Intestinal Ischemia
Published on: May 18, 2018
Microbial regulation of intestinal stem cell function: implications for alleviating intestinal injury of weaned
Bo Song1,2, Feilong Deng1, Hui Jiang1
1Guangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Animal Science and Technology, Foshan University, Foshan, 528225, China.
Abstract:
This review highlights how gut microbiota regulates intestinal stem cell function. Weaning stress disrupts this balance, causing intestinal injury in piglets. However, targeted nutritional interventions can modulate the gut microbiota to restore ISC function and repair tissue damage. Understanding this microbe-ISC interaction provides new, effective strategies to improve gut health and alleviate weaning-induced injury in animals.
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