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Updated: Apr 7, 2026

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression
Published on: January 7, 2019
Case Report: Right-sided vagus nerve stimulation for treatment-resistant affective disorders with complex cardiac
Christiane Licht1, Michael Landgrebe2,3, Tom Pieper4
1Department of Psychiatry, Psychotherapy and Psychosomatics, Rheinisch-Westfälische Technische Hochschule (RWTH) University Clinic, Aachen, Germany.
Right-sided vagus nerve stimulation (VNS) effectively stabilized mood in three patients with treatment-resistant depression. This approach reduced hospitalizations and was well-tolerated, showing promise for psychiatric care.
Area of Science:
- Neuroscience
- Psychiatry
- Medical Devices
Background:
- Vagus nerve stimulation (VNS) is established for treatment-resistant affective disorders.
- Right-sided VNS is rarely used due to cardiac concerns, limiting psychiatric data.
- Left-sided implantation is standard practice.
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