Lymph Node Mapping in Urethral Transitional Cell Carcinoma: A Case Report

Primary urethral carcinoma is an uncommon malignancy, representing <1% of all urologic cancers. Lymph node staging is an integral part of urethral carcinomas; however, sentinel node mapping has not been reported in this malignancy before for urethral transitional carcinoma (TCC). We report a 77-year-old woman with urethral transitional cell carcinoma in whom SLNB revealed bilateral inguinal lymph node involvement. Although frozen section analysis confirmed metastasis, final surgical pathology demonstrated no residual primary tumor. This case illustrates the clinical utility of SLNB in detecting occult nodal disease and its role in guiding surgical management of urethral carcinoma.