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The lower urinary system consists of the urinary bladder and urethra, which are essential in storing and expelling urine from the body. Together with the internal and external sphincters, these structures work together to regulate urination effectively.Anatomy of the BladderThe urinary bladder is a muscular, stretchable organ behind the pubic bone and in front of the rectum. In females, the bladder is positioned anterior to the vagina and inferior to the uterus, while in males, it is located...

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Updated: Apr 7, 2026

Technical Modification of the Terminal Ureter During Total Transperitoneal Laparoscopic Nephroureterectomy for Upper Urinary Tract Urothelial Carcinoma

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Published on: November 22, 2019

Lymph Node Mapping in Urethral Transitional Cell Carcinoma: A Case Report.

Pegah Sahafi¹, Zahra Kiamanesh², Mohammad Hadi Samadi¹

¹Nuclear Medicine Research Center, Mashhad University of Medical Science, Mashhad, Iran.

Clinical Nuclear Medicine

|April 6, 2026

Summary

Sentinel lymph node biopsy (SLNB) is a novel technique for staging urethral transitional cell carcinoma (TCC). This study shows SLNB can detect occult lymph node metastasis, guiding treatment for this rare cancer.

Area of Science:

Urology
Oncology
Surgical Pathology

Background:

Primary urethral carcinoma is a rare malignancy, accounting for less than 1% of urologic cancers.

Keywords:

SPECT/CT lymphoscintigraphy sentinel lymph node transitional cell carcinoma urethral cancer

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Accurate lymph node staging is crucial for managing urethral carcinomas.

Sentinel lymph node biopsy (SLNB) has not been previously reported for urethral transitional cell carcinoma (TCC).