Related Experiment Video
Updated: Apr 8, 2026

Quantification of Humic and Fulvic Acids in Humate Ores, DOC, Humified Materials and Humic Substance-Containing Commercial Products
Published on: March 18, 2022
Pharmacological Effects of Humic Substances and the Signaling Mechanisms of Their Implementation
T V Lasukova1, M V Zykova2, E S Trofimova2
1Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia. tlasukova@mail.ru.
Abstract:
The analysis of current data and our own research findings have shown that humic substances represent a promising group of natural compounds with diverse pharmacological properties, including immunotropic, cardio-, neuro-, hepatoprotective, vasodilatory, antibacterial, and antiviral effects. The review presents information on therapeutic applications of humic substances derived from various sources and pharmaceutical preparations based on them in the treatment of diabetes, HIV infection, myocardial and cerebral ischemia, colitis, and some other pathological conditions. Research on the pro-apoptotic and anti-melanogenic effects of these compounds will enhance the effectiveness of existing approaches in the treatment of malignant tumors. This review presents data on the use of humic substances for developing novel drug delivery systems with tailored functionalities as a promising strategy in clinical oncology. Humic acids from peat exhibit stress-relief activity comparable to that of standard medications and preventive effects against exercise-induced fatigue. The review analyzes the intracellular mechanisms that play a key role in the realization of the effects of humic substances.
More Related Videos
Related Concept Videos
Hedgehog Signaling Pathway
Hedgehog Signaling Pathway
Chemical Signaling in the Endocrine System
Lipid-soluble hormones, such as steroid hormones, demonstrate an intracellular action. These hormones traverse cell membranes due to their lipid nature. Once inside the target cell, they...
Signal Transduction: Overview
Typically, signal transduction involves three...
Principles of Drug Action
Drugs can be agonists or antagonists. Like the endogenous ligands, agonists always bind and activate the target to produce a cellular response. Agonist binding induces a conformational change which in turn...
Cell Signaling in Plants

