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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

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Total Synthesis of Indigotinoline A and Enabled Stereochemical Revision of Isatindigotindoline B

Jiaji Li1,2, Zhibin Zhao3,4,5, Peiyuan Yang1,2

  • 1Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development,Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, P. R. China.

Organic Letters
|April 8, 2026
PubMed

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