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Updated: Apr 14, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
08:13

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

Published on: February 16, 2016

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Cardiac CT for the Assessment of Ischemic Cardiomyopathy

Ji Won Lee, Eun-Ju Kang, Sung Ho Hwang

    Journal of the Korean Society of Radiology
    |April 13, 2026
    PubMed

    Insights

    Cardiac CT offers comprehensive assessment for ischemic cardiomyopathy, evaluating ischemia, infarction, and tissue characteristics. This multiparametric approach aids in differentiating cardiac conditions and guiding treatment decisions.

    Area of Science:

    • Cardiology
    • Radiology
    • Medical Imaging

    Background:

    • Ischemic cardiomyopathy is a primary cause of heart failure.
    • Accurate assessment of myocardial ischemia, infarction, and tissue properties is crucial for treatment.
    • Cardiac CT offers integrated structural and functional evaluation.

    Purpose of the Study:

    • To review the role of cardiac CT in evaluating ischemic cardiomyopathy.
    • To highlight advances in CT techniques for myocardial assessment.
    • To emphasize the multiparametric capabilities of cardiac CT.

    Main Methods:

    • Coronary anatomical evaluation using Cardiac CT.
    • Assessment of left ventricular volume, ejection fraction, and regional wall motion.
    • CT myocardial perfusion imaging for ischemia, late iodine enhancement CT for infarction/fibrosis, and dual-energy CT for tissue characterization (e.g., extracellular volume).
    • CT-derived fractional flow reserve for physiological assessment of coronary stenosis.

    Main Results:

    • Cardiac CT provides integrated structural and functional information.
    • CT myocardial perfusion imaging evaluates hemodynamically significant ischemia.
    • Late iodine enhancement CT visualizes myocardial infarction and fibrosis.
    • Dual-energy CT enhances tissue characterization and quantitative analysis.
    • Integration of multiparametric CT findings improves differentiation of cardiomyopathies.

    Conclusions:

    • Cardiac CT has become a multiparametric platform for myocardial evaluation in ischemic cardiomyopathy.
    • Advanced CT techniques enable comprehensive assessment of myocardial ischemia, infarction, and tissue characteristics.
    • These integrated findings are essential for therapeutic decision-making in heart failure management.

    Keywords:
    CT Myocardial PerfusionCardiac CTCardiac FunctionIschemic CardiomyopathyLate Iodine Enhancement

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