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Author Spotlight: Developing Precise and Clinically Relevant Models for Studying Secondary Degeneration in Traumatic Optic Neuropathy
Published on: November 29, 2024
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Traumatic Brain Injury and Its Ophthalmologic Implications.
Vlad Liviu Hârtie1,2, Nicoleta Anton1,3, Otilia Boișteanu1,3
1"Gr. T. Popa" University of Medicine and Pharmacy, Iași, Romania.
Romanian Journal of Ophthalmology
|April 13, 2026
Summary
Traumatic brain injury (TBI) often causes vision problems affecting the eyes, optic nerve, and brain. Early recognition and treatment of these visual deficits are crucial for recovery.
Area of Science:
- Ophthalmology
- Neurology
- Neuroscience
Background:
- Traumatic brain injury (TBI) commonly leads to visual pathway dysfunctions.
- Symptoms range from reduced visual acuity and fields to optic neuropathy and oculomotor deficits.
- Underdiagnosis is prevalent despite treatable visual deficits.
Purpose of the Study:
- To highlight the importance of recognizing visual symptoms post-TBI.
- To discuss current diagnostic and therapeutic challenges.
- To explore the potential of advanced imaging in TBI research.
Main Methods:
- Review of visual symptoms and their impact on the visual pathway.
- Discussion of diagnostic and management strategies.
- Introduction of advanced imaging techniques like SD-OCTA.
Main Results:
- TBI affects visual acuity, visual fields, optic nerve, and oculomotor control.
- Photophobia and visuo-perceptual issues are also common.
- SD-OCTA offers noninvasive quantification of retinal vasculature.
Conclusions:
- Ophthalmologists and optometrists must recognize TBI-related visual symptoms.
- Standardized protocols and rehabilitation studies are needed.
- Novel imaging may provide insights into TBI's neural and vascular pathology.
Keywords:
CSF = cerebrospinal fluidCTE = chronic traumatic encephalopathyIVMP = intravenous methylprednisoloneRNFL = retinal nerve fiber layerSD-OCTA = spectral domain optical coherence tomographyTBI = traumatic brain injuryTON = traumatic optic neuropathychronic traumatic encephalopathydLGN = dorsal lateral geniculate nucleustraumatic brain injurytraumatic optic neuropathy
