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Using Robotic Systems to Process and Embed Colonic Murine Samples for Histological Analyses
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Collaborative Robotic Systems for Pre-Analytical Processing of Biological Specimens in a Medical Laboratory.

Andrey G Komarov1, Pavel O Bochkov1, Arkadiy S Goldberg2

  • 1Moscow Scientific and Practical Center for Laboratory Research, Moscow 125424, Russia.

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|April 14, 2026
PubMed
Summary

Collaborative robots (cobots) significantly reduce labor in medical labs by automating pre-analytical tasks. While improving efficiency, human operators remain faster at specific procedures like aliquoting.

Keywords:
IVD managementclinical laboratorycollaborative robotsefficiency indicatorshealthcare

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Area of Science:

  • Medical Laboratory Science
  • Robotics in Healthcare
  • Automation and Workflow Optimization

Background:

  • Increasing laboratory test volumes and quality standards necessitate automation.
  • Conventional Total Laboratory Automation (TLA) systems face cost and integration challenges.
  • Collaborative robots (cobots) offer a flexible solution for pre-analytical and logistical tasks.

Purpose of the Study:

  • To systematically integrate commercial cobots into a large centralized laboratory's pre-analytical workflow.
  • To evaluate the impact of cobot integration on labor input and operational efficiency.
  • To assess the performance of cobots in specific pre-analytical tasks.

Main Methods:

  • Integration of specialized cobot modules (decapping, barcode handling, analyzer loading, aliquoting, sorting).
  • Bidirectional integration with the Laboratory Information System (LIS).
  • Evaluation of architectural design, control algorithms, labor, and turnaround time.

Main Results:

  • 87% reduction in labor input.
  • 3.4% improvement in liquid aliquoting accuracy.
  • Enhanced nominal throughput, though human operators were 42.5% faster in aliquoting.

Conclusions:

  • Cobots show promise for operational efficiency and flexibility in centralized medical labs.
  • Further studies are needed to assess the impact on test quality/accuracy and generalizability.
  • Cobots offer a viable alternative to traditional automation and manual workflows.