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Updated: Apr 15, 2026

Structural Characterization of Mannan Cell Wall Polysaccharides in Plants Using PACE

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Published on: October 16, 2017

Multifunctional Konjac Glucomannan Film Tuning by Gallic Acid Functionalization.

Lidia Zasada¹, Marcin Wekwejt², Marta Michalska-Sionkowska³

¹Laboratory for Functional Polymeric Materials, Faculty of Chemistry, Nicolaus Copernicus University in Toruń, Gagarina 7, 87-100 Torun, Poland.

|April 14, 2026

Summary

Gallic acid (GA) functionalization enhances konjac glucomannan (KG) films, improving mechanical strength, antioxidant activity, and hydration control. These modified KG films show promise for biomedical uses like wound dressings.

Keywords:

functionalization gallic acid konjac glucomannan packing materials wound dressing

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Area of Science:

Biomaterials Science
Polymer Chemistry
Materials Engineering

Background:

Konjac glucomannan (KG) is a biocompatible polysaccharide with inherent limitations in functional performance.
Modification strategies are essential to enhance the properties of KG for advanced applications.

Purpose of the Study:

To investigate the impact of gallic acid (GA) functionalization on the structural, physicochemical, mechanical, antioxidant, and biological properties of KG-based films.
To evaluate the potential of GA-modified KG films for biomedical applications.

Main Methods:

Fourier-transform infrared (FTIR) spectroscopy to confirm GA-KG interactions.
Physicochemical characterization including surface energy, roughness, hydration, and water vapor permeability.
Mechanical testing (tensile strength, elongation), antioxidant activity assays, hemocompatibility, and cytocompatibility evaluations.

Main Results:

GA functionalization via non-covalent hydrogen bonding improved KG film properties without altering the polymer backbone.
Concentration-dependent tuning of surface energy, roughness, hydration, and water vapor permeability was achieved.
Significant enhancements in stiffness, tensile strength, and antioxidant activity were observed, alongside excellent hemocompatibility and content-dependent cytocompatibility.

Conclusions:

GA modification effectively enhances the functional performance of KG films, preserving polymer integrity.
GA-modified KG films demonstrate potential for biomedical applications, particularly wound dressings, due to improved antioxidant activity, controlled hydration, and biocompatibility.