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Canal Cholesteatoma Presentation and Management: A Systematic Review and Meta-Analysis
Angelica M Walker1, Matthew Cheung1, Shaun A Nguyen1
1Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA.
Summary
External auditory canal cholesteatoma (EACC) is often diagnosed late. Recognizing risk factors like nicotine use and symptoms such as ear pain can speed up detection and treatment, leading to good outcomes.
Area of Science:
- Otolaryngology
- Dermatology
- Medical Research
Background:
- External auditory canal cholesteatoma (EACC) presents diagnostic and management challenges.
- Delayed diagnosis of EACC can lead to increased morbidity.
Purpose of the Study:
- To review the current understanding of EACC, including its symptoms, clinical presentation, and treatment.
- To identify strategies to reduce diagnostic delays for EACC.
Main Methods:
- A comprehensive literature search was conducted across PubMed, CINAHL, Cochrane Library, and SCOPUS.
- Meta-analyses were performed on data from 30 studies involving 1007 patients diagnosed with EACC.
Main Results:
- The majority of patients (60.7%) were diagnosed with Stage III EACC.
- Common risk factors included nicotine use (33.1%) and cotton swab abuse (24.3%).
- Otalgia (39.9%) and otorrhea (50.3%) were frequent symptoms, but 15.7% were asymptomatic. Treatment involved conservative measures and surgical interventions like canalplasty (68.6%), with low recurrence rates (4.5%).
Conclusions:
- EACC is frequently diagnosed at advanced stages, underscoring the need for early recognition.
- Identifying key risk factors and symptoms is crucial for timely diagnosis and effective management.
- Tailored interventions can achieve low recurrence rates and mitigate the impact of delayed diagnosis.
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