Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Confocal Fluorescence Microscopy

Confocal Fluorescence Microscopy

Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Respiratory-physiology modeling of therapeutic hydrogen inhalation: defining the fraction of inspired hydrogen (FiH<sub>2</sub>) and flow-rate requirements.

Respiratory research·2026

Same author

Exploring the human small intestinal luminal microbiome via a newly developed ingestible sampling device.

ISME communications·2025

Same author

Profiling the human luminal small intestinal microbiome using a novel ingestible medical device.

medRxiv : the preprint server for health sciences·2025

Same author

Molecular hydrogen as a potential mediator of the antitumor effect of inulin consumption.

Scientific reports·2025

Same author

Molecular Hydrogen for Outpatients with COVID-19 (Hydro-COVID): A Phase 3 Randomised, Triple-Blinded, Pragmatic, Placebo-Controlled, Multicentre Trial.

Journal of clinical medicine·2024

Same author

Piezoelectric Micromachined Microphone with High Acoustic Overload Point and with Electrically Controlled Sensitivity.

Micromachines·2024

Same journal

Deep learning-based dose prediction to enhance planning efficiency in cervical brachytherapy with hybrid applicators.

Physics in medicine and biology·2026

Same journal

Corrigendum: Referenceless MR thermometry-a comparison of five methods (2017<i>Phys. Med. Biol</i>.<b>62</b>1-16).

Physics in medicine and biology·2026

Same journal

Corrigendum: Measured and Monte Carlo simulated electron backscatter to the monitor chamber for the varian TrueBeam linac (2016<i>Phys. Med. Biol</i>.<b>61</b>8779).

Physics in medicine and biology·2026

Same journal

Corrigendum: 3D range-modulator for scanned particle therapy: development, Monte Carlo simulations and experimental evaluation (2017<i>Phys. Med. Biol</i>.<b>62</b>7075).

Physics in medicine and biology·2026

Same journal

Recent progress in applications of computing to radiotherapy (ICCR 2016).

Physics in medicine and biology·2026

Same journal

Novel TMS coils designed using an inverse boundary element method.

Physics in medicine and biology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Apr 17, 2026

Author Spotlight: Advancing Knowledge in Far-From-Equilibrium Materials Through Light-Sheet Microscopy

Author Spotlight: Advancing Knowledge in Far-From-Equilibrium Materials Through Light-Sheet Microscopy

Published on: January 26, 2024

Curved-slit collimation for fan-beam-based virtual fluoroscopy.

Laurent Desbat¹, Odran Pivot¹, Patrick Pittet²

¹Université Grenoble Alpes, CNRS, UMR 5525, VetAgro Sup, Grenoble INP, TIMC, 38000 Grenoble, France.

Physics in Medicine and Biology

|April 15, 2026

Summary

This summary is machine-generated.

New curved-slit collimation significantly improves virtual fluoroscopy by reducing radiation exposure during interventional radiology. This fan-beam technology enhances precision and addresses limitations of previous straight-slit designs.

Keywords:

rotating collimator shape optimization virtual fluoroscopy x-ray dose reduction.

More Related Videos

High Speed Sub-GHz Spectrometer for Brillouin Scattering Analysis

High Speed Sub-GHz Spectrometer for Brillouin Scattering Analysis

Published on: December 22, 2015

Video-rate Scanning Confocal Microscopy and Microendoscopy

Video-rate Scanning Confocal Microscopy and Microendoscopy

Published on: October 20, 2011

Related Experiment Videos

Last Updated: Apr 17, 2026

Author Spotlight: Advancing Knowledge in Far-From-Equilibrium Materials Through Light-Sheet Microscopy

Author Spotlight: Advancing Knowledge in Far-From-Equilibrium Materials Through Light-Sheet Microscopy

Published on: January 26, 2024

High Speed Sub-GHz Spectrometer for Brillouin Scattering Analysis

High Speed Sub-GHz Spectrometer for Brillouin Scattering Analysis

Published on: December 22, 2015

Video-rate Scanning Confocal Microscopy and Microendoscopy

Video-rate Scanning Confocal Microscopy and Microendoscopy

Published on: October 20, 2011

Area of Science:

Medical Imaging
Radiological Physics

Background:

Interventional radiology procedures involve significant radiation exposure for patients and physicians.
Virtual fluoroscopy using fan-beams offers a method to reduce this irradiation.
Previous fan-beam approaches utilized straight-slit collimation.

Purpose of the Study:

To demonstrate the benefits of curved-slit collimation for fan-beam generation in virtual fluoroscopy.
To compare the performance of curved-slit collimation against straight-slit collimation.
To develop a framework for analyzing and optimizing collimator slit geometry.

Main Methods:

Studied spiral-slits enabling localization procedures similar to straight-slits.
Analyzed the dependence of localization error on slit shape and established error bounds.
Evaluated performance of various curved-slit geometries using numerical experiments and X-ray equipment tests.

Main Results:

Curved-slit geometries demonstrated systematic performance improvements over straight-slits.
A specific curved-slit design (linear spiral and exponential parts) reduced localization error.
The proposed curved-slit geometry resolved the blind central zone issue inherent in straight-slit designs.

Conclusions:

Developed a framework for analyzing localization error amplification in rotating collimators with spiral-slits.
Established criteria and bounds for optimizing slit geometry based on performance.
The framework is adaptable for comparing collimator slits under diverse operating conditions.