Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Urinary Tract Calculi VI: Surgical Management01:25

Urinary Tract Calculi VI: Surgical Management

941
Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...
941
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

463
Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
463

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Trends in Industry-Sponsored Research Payments to Otolaryngologist Principal Investigators.

The Laryngoscope·2026
Same author

Presentation, management, and outcomes of testicular germ cell tumors by age.

Urologic oncology·2026
Same author

Reply by Authors.

The Journal of urology·2026
Same author

Optimizing ChatGPT: Applying prompt engineering to frequently asked questions in urologic oncology.

Canadian Urological Association journal = Journal de l'Association des urologues du Canada·2026
Same author

Barriers to Health Care Access and Use Among Racial and Ethnic Minorities With Renal Cell Carcinoma.

Urology practice·2026
Same author

Survival outcomes after surgical treatment for non-clear cell renal cell carcinoma with tumor thrombus extension: a population-based cohort study.

World journal of urology·2026

Related Experiment Video

Updated: Apr 17, 2026

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance
05:19

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance

Published on: November 7, 2025

1.1K

Surgical Management of High-Risk Prostate Cancer.

Joseph G Cheaib1, Mohamad E Allaf1

  • 1Department of Urology, The James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, 600 N. Wolfe Street, Baltimore, MD 21287, USA.

The Urologic Clinics of North America
|April 15, 2026
PubMed
Summary
This summary is machine-generated.

Radical prostatectomy (RP) is an effective treatment for high-risk prostate cancer (HRPCa), offering an alternative to combined therapies. Advances in surgical techniques improve outcomes and reduce morbidity for select HRPCa patients.

Keywords:
Functional outcomesHigh-riskOncologic outcomesProstate cancerProstatectomyTechnique

More Related Videos

Retzius-Sparing Robot-Assisted Radical Prostatectomy
12:10

Retzius-Sparing Robot-Assisted Radical Prostatectomy

Published on: May 19, 2022

10.0K
Surgical Treatment for Benign Prostatic Hyperplasia: Holmium Laser Enucleation of the Prostate HoLEP.
06:04

Surgical Treatment for Benign Prostatic Hyperplasia: Holmium Laser Enucleation of the Prostate HoLEP.

Published on: March 6, 2018

17.9K

Related Experiment Videos

Last Updated: Apr 17, 2026

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance
05:19

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance

Published on: November 7, 2025

1.1K
Retzius-Sparing Robot-Assisted Radical Prostatectomy
12:10

Retzius-Sparing Robot-Assisted Radical Prostatectomy

Published on: May 19, 2022

10.0K
Surgical Treatment for Benign Prostatic Hyperplasia: Holmium Laser Enucleation of the Prostate HoLEP.
06:04

Surgical Treatment for Benign Prostatic Hyperplasia: Holmium Laser Enucleation of the Prostate HoLEP.

Published on: March 6, 2018

17.9K

Area of Science:

  • Urology
  • Oncology
  • Surgical Oncology

Background:

  • High-risk prostate cancer (HRPCa) is a complex disease with diverse clinical behaviors.
  • Historically, radiotherapy combined with androgen deprivation therapy was standard for HRPCa.
  • Radical prostatectomy (RP) is increasingly recognized as a primary treatment option.

Purpose of the Study:

  • To evaluate the efficacy and safety of radical prostatectomy (RP) in managing high-risk prostate cancer (HRPCa).
  • To highlight the role of advancements in imaging and surgical techniques in personalizing HRPCa treatment.
  • To discuss the potential of RP to mitigate adverse effects associated with combined therapies.

Main Methods:

  • Review of emerging evidence supporting RP in select HRPCa patients.
  • Analysis of advancements in diagnostic imaging for precise surgical planning.
  • Assessment of modern surgical techniques to minimize RP-related morbidity.
  • Consideration of ongoing clinical trials investigating RP in multimodal settings.

Main Results:

  • Radical prostatectomy (RP) demonstrates effectiveness in select high-risk prostate cancer (HRPCa) cases.
  • Improved imaging and surgical techniques reduce RP morbidity while maintaining oncologic control.
  • RP may help patients avoid the adverse effects of combined radiotherapy and androgen deprivation therapy.

Conclusions:

  • Radical prostatectomy (RP) is a viable and effective primary treatment for carefully selected high-risk prostate cancer (HRPCa) patients.
  • Personalized surgical care through advanced techniques enhances RP outcomes for HRPCa.
  • Further research and ongoing trials will define the optimal role of RP in multimodal treatment strategies for HRPCa.