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Patient Factors Associated with Presacral Space Depth: A Pelvic MRI Study
Krystine Gulbrand1, Amanda Chapa1, Mariana Masteling2
1Division of Urogynecology, Indiana University School of Medicine, Indianapolis, IN, USA.
International Urogynecology Journal
|April 16, 2026
Summary
Body mass index (BMI) does not predict presacral space depth in women undergoing sacrocolpopexy. Prior hysterectomy, however, is associated with increased presacral depth, impacting surgical planning for pelvic organ prolapse.
Area of Science:
- Urogynecology
- Pelvic Reconstructive Surgery
- Anatomical Studies
Background:
- Sacrocolpopexy is a durable repair for advanced pelvic organ prolapse.
- Dissection of the presacral space is a critical yet challenging step.
- Patient-specific factors influencing presacral anatomy require further investigation.
Purpose of the Study:
- To investigate patient-specific factors, particularly body mass index (BMI), associated with variations in presacral space depth.
- To identify anatomical variations relevant to sacrocolpopexy surgical planning.
Main Methods:
- Retrospective cohort study analyzing pelvic MRI scans (n=167) in women.
- Standardized midsagittal MRI technique to measure presacral depth, ligament thickness, and sacral dimensions (L5-S3).
- Correlation analyses between anatomical measurements and patient demographics/clinical characteristics.
Main Results:
- BMI showed weak correlation with presacral space depth.
- History of hysterectomy was linked to a 24% increase in presacral depth at S1 (p=0.01).
- Postmenopausal status and estrogen use correlated with increased L5-S1 disc space height.
Conclusions:
- Presacral space depth is not significantly influenced by BMI.
- Prior hysterectomy is a key factor associated with altered presacral anatomy.
- These findings are relevant for optimizing surgical planning in sacrocolpopexy.
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