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Updated: Apr 21, 2026

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice
Published on: June 28, 2021
Suspected Chromium-Induced Acute Pancreatitis: Highlighting the Risks of Over-the-Counter Supplements
Yusuf Kagzi1, Preethi L Chintagunta1, Saurabh K Bansal1
1Department of Internal Medicine, University of Illinois College of Medicine, Peoria, IL.
Abstract:
Drug-induced pancreatitis accounts for a small percentage of acute pancreatitis cases, and supplement-induced cases are poorly characterized. We report a 59-year-old woman presenting with acute interstitial pancreatitis after recent initiation of an over-the-counter supplement containing chromium polynicotinate and herbal additives. She lacked traditional risk factors, and imaging showed no biliary disease. Lipase exceeded 3000 U/L, and serum chromium was elevated (0.5 ng/mL). Symptoms improved with supportive care and supplement discontinuation. This case suggests a potential association between chromium-containing supplements and pancreatitis, highlighting the need for thorough supplement histories in idiopathic cases and greater awareness of possible pancreatic toxicity from nutraceuticals.
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