Related Experiment Video
Updated: Apr 22, 2026
08:12
Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants
Published on: March 29, 2018
10.9K
Aphrodisiac Drug and Dental Health: A Systematic Review
M R Murali1, Kolasani Balaram2, Rahul Tiwari3
1Department of Psychiatry, JSS Academy of Higher Education and Research, Mysore, Karnataka, India.
Journal of Pharmacy & Bioallied Sciences
|April 20, 2026
Summary
Aphrodisiac drugs like sildenafil and ginseng show potential benefits for oral health, including reduced inflammation and improved periodontal health. Further research is needed to confirm their effectiveness in dental care.
Area of Science:
- Pharmacology
- Periodontology
- Oral Health
Background:
- Aphrodisiac drugs, including synthetic (e.g., sildenafil) and herbal (e.g., ginseng) agents, are commonly used for sexual enhancement.
- Emerging evidence suggests a potential impact of these agents on oral and periodontal health, an area requiring systematic investigation.
Purpose of the Study:
- To systematically evaluate the effects of aphrodisiac drugs on dental and oral health outcomes.
- To synthesize current evidence on the relationship between aphrodisiac agents and oral health.
Main Methods:
- Systematic review adhering to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.
- Comprehensive literature search across major databases (PubMed, Scopus, Web of Science, Google Scholar) from 2000 to 2025.
- Inclusion of original studies reporting oral health outcomes associated with aphrodisiac drug use, encompassing preclinical and clinical research.
Main Results:
- Sildenafil demonstrated potential in reducing alveolar bone loss and inflammation in preclinical models.
- Ginseng-derived compounds (ginsenosides) exhibited significant anti-inflammatory, antimicrobial, and osteogenic properties.
- A clinical trial indicated red ginseng mouth rinse efficacy comparable to chlorhexidine in plaque control, suggesting promise for periodontitis management.
Conclusions:
- Both synthetic and herbal aphrodisiac agents possess potential benefits for oral health, particularly in periodontal therapy.
- Ginseng-derived compounds show promise for managing periodontitis and maintaining oral health.
- Further clinical trials are necessary to validate the safety, efficacy, and practical application of these agents in dental care.
Related Concept Videos
01:27Combined Effects of Drugs: Synergism
5.9K
Synergism is a useful mechanism where combining two or more drugs is more effective than each constituent used alone. Such combinations are also called supra-additive interactions. The drugs collectively enhance the final therapeutic effect by acting on different targets. Another advantage is that the low dose of each constituent drug is sufficient to achieve the desired effect. This helps reduce the duration of therapy and lower the adverse effects of these drugs.
Such synergistic combinations...
Such synergistic combinations...
5.9K
01:23Antihypertensive Drugs: Vasodilators
2.5K
Vasodilators, primarily affecting the smooth muscles within arterial and venous walls, are commonly used for hypertension treatment. Medications such as minoxidil and hydralazine primarily target arteries and arterioles, while sodium nitroprusside acts on arterioles and venules. Minoxidil, functioning as a prodrug, is metabolized by hepatic sulfotransferase into its active form, minoxidil sulfate, after oral administration. This metabolite binds to the sulfonylurea receptor (SUR) component of...
2.5K
01:26Assessment of the Mouth
1.6K
A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
1.6K
01:26Pharmacokinetics: Drug–Food and Drug–Viral Interactions
665
A drug interaction occurs when the concurrent use of another drug, food, or an external substance alters the pharmacological activity of a drug. This interaction can modify the action of the original drug, affecting its effectiveness and safety.Drug–food interactions are significant as they impact drug absorption, metabolism, and excretion. For example, grapefruit juice is a well-known disruptor of drug metabolism. It inhibits the cytochrome P450 3A4 enzyme, crucial for the metabolism of...
665
01:27Pharmacodynamics in Geriatric Patients: Effects of Age
354
Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
354
01:08Effect of Hepatic Disease on Pharmacokinetics: Dose Adjustments Due to Hepatic Impairment
377
Hepatic impairment, characterized by decreased liver function, does not uniformly mandate adjustments in drug dosage. Whether dosage modifications are necessary depends on various factors related to the drug's metabolism and elimination pathways. If a drug is primarily excreted via the kidneys and bypasses significant hepatic processing, if it undergoes minimal metabolic transformation in the liver, or if it is volatile and primarily expelled through the lungs, dose adjustments may not be...
377