Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

485
Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
485
Myocarditis I: Introduction01:21

Myocarditis I: Introduction

631
Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
631
Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

999
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
999
Pericarditis I: Introduction01:22

Pericarditis I: Introduction

737
Pericarditis is defined as the inflammation of the pericardium, the thin, sac-like membrane surrounding the heart. This condition can cause significant chest pain and other symptoms, often necessitating medical intervention. The pericardium has two layers: the inner visceral layer and the outer parietal layer, separated by a small amount of fluid that reduces friction during heartbeats.Types of PericarditisPericarditis can be classified into several types based on the duration and nature of the...
737
Pericarditis II: Clinical Features and Diagnostic Tests01:19

Pericarditis II: Clinical Features and Diagnostic Tests

615
Pericarditis is distinguished by inflammation of the pericardium, the fibrous sac that encases the heart. It can be acute, lasting less than six weeks, or chronic, persisting for over three months. Understanding its clinical manifestations and diagnostic findings is crucial for timely and effective management.Clinical ManifestationsWhile pericarditis can be asymptomatic, it usually presents with characteristic symptoms such as:Chest Pain: The most characteristic symptom of pericarditis is chest...
615
Myocarditis III: Medical Management01:14

Myocarditis III: Medical Management

341
Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
341

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Corrosion inhibition of ductile iron in hydrochloric acid using 5-amino-1,3,4-thiadiazole-2-thiol: electrochemical and computational studies.

Scientific reports·2026
Same author

AI-driven discovery in protein science for immunology and infectious disease research.

Frontiers in bioinformatics·2026
Same author

Intraoperative application of FFR pressure wire and FLOW800 imaging as predictors of postoperative cerebral perfusion abnormalities in Moyamoya disease.

Frontiers in surgery·2026
Same author

Systems biology in the era of AI: "winter" or "evolution"?

Frontiers in systems biology·2026
Same author

Experimental assessment of AI-based interactome mapping.

Nature communications·2026
Same author

The "FAST" bypass philosophy: a framework for precision in superficial temporal artery to middle cerebral artery revascularization after 17,000 cases.

Journal of neurosurgical sciences·2026
Same journal

Nutritional Management of Beef Stocker Calves in Grazing Systems.

The Veterinary clinics of North America. Food animal practice·2026
Same journal

Strategies for Data-Driven Investigations of Disease and Decreased Production on Stocker Operations.

The Veterinary clinics of North America. Food animal practice·2026
Same journal

Nonrespiratory Diseases of Stocker Cattle.

The Veterinary clinics of North America. Food animal practice·2026
Same journal

The Role of Early Handling Experiences on the Welfare of Beef Stocker Cattle.

The Veterinary clinics of North America. Food animal practice·2026
Same journal

Stocker Production Medicine: An Emerging Area of Specialization in Modern Food Animal Practice.

The Veterinary clinics of North America. Food animal practice·2026
Same journal

Immunology of Beef Stocker Cattle.

The Veterinary clinics of North America. Food animal practice·2026
See all related articles

Related Experiment Video

Updated: Apr 23, 2026

Isolation and Characterization of Cardiac Mesenchymal Stromal Cells from Endomyocardial Bioptic Samples of Arrhythmogenic Cardiomyopathy Patients
09:16

Isolation and Characterization of Cardiac Mesenchymal Stromal Cells from Endomyocardial Bioptic Samples of Arrhythmogenic Cardiomyopathy Patients

Published on: February 28, 2018

9.7K

Histophilosis Myocarditis and Pericarditis.

Joyce Van Donkersgoed1, Bruce Hill2, Steve Hendrick3

  • 1Dr. Joyce Van Donkersgoed Inc., Coaldale, Canada.

The Veterinary Clinics of North America. Food Animal Practice
|April 21, 2026
PubMed
Summary
This summary is machine-generated.

Histophilosis causes significant mortality in feedlot calves, particularly myocarditis and pericarditis. Current vaccines are ineffective, necessitating research into genetic virulence factors for improved subunit vaccines.

Keywords:
EndocarditisHistophilus somniMyocarditisPericarditisPulmonary edema

More Related Videos

Sterile Pericarditis in Aachener Minipigs As a Model for Atrial Myopathy and Atrial Fibrillation
08:56

Sterile Pericarditis in Aachener Minipigs As a Model for Atrial Myopathy and Atrial Fibrillation

Published on: September 24, 2021

2.5K
An Intact Pericardium Ischemic Rodent Model
07:15

An Intact Pericardium Ischemic Rodent Model

Published on: September 2, 2021

2.2K

Related Experiment Videos

Last Updated: Apr 23, 2026

Isolation and Characterization of Cardiac Mesenchymal Stromal Cells from Endomyocardial Bioptic Samples of Arrhythmogenic Cardiomyopathy Patients
09:16

Isolation and Characterization of Cardiac Mesenchymal Stromal Cells from Endomyocardial Bioptic Samples of Arrhythmogenic Cardiomyopathy Patients

Published on: February 28, 2018

9.7K
Sterile Pericarditis in Aachener Minipigs As a Model for Atrial Myopathy and Atrial Fibrillation
08:56

Sterile Pericarditis in Aachener Minipigs As a Model for Atrial Myopathy and Atrial Fibrillation

Published on: September 24, 2021

2.5K
An Intact Pericardium Ischemic Rodent Model
07:15

An Intact Pericardium Ischemic Rodent Model

Published on: September 2, 2021

2.2K

Area of Science:

  • Veterinary Medicine
  • Bacterial Diseases
  • Cattle Health

Background:

  • Histophilosis is a multisystemic bacterial disease impacting feedlot cattle.
  • Common manifestations include bronchopneumonia, laryngitis, otitis, pleuritis, myocarditis, pericarditis, endocarditis, polyarthritis, and infectious thrombomeningoencephalitis.
  • Myocarditis and pericarditis are prevalent in western Canada, leading to substantial calf mortality.

Purpose of the Study:

  • To address the significant mortality caused by Histophilosis in feedlot cattle.
  • To highlight the limitations of current diagnostic methods and treatments.
  • To guide future research towards developing effective vaccines.

Main Methods:

  • Diagnosis relies on gross pathological lesions.
  • No validated live animal tests with high predictive value are currently available.
  • Evaluation of licensed Histophilus somni bacterins showed no proven efficacy in reducing mortality.

Main Results:

  • Histophilosis leads to severe multisystemic infections in feedlot cattle.
  • Myocarditis and pericarditis are key contributors to mortality in fall-placed calves.
  • Existing bacterins fail to effectively reduce disease-related mortality.

Conclusions:

  • Effective live animal diagnostics for Histophilosis are lacking.
  • Current bacterins do not prevent mortality.
  • Further research into strain genetic virulence is crucial for developing effective subunit vaccines against this costly feedlot disease.