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[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst
Published on: May 21, 2019
Photocatalytic Oxidative Generation and Synthetic Application of Phosphine-Boryl Radicals
Yu Matsuda1, Takahito Kuribara1,2, Tetsuhiro Nemoto1
1Graduate School of Pharmaceutical Sciences, Chiba University, 1-8-1, Inohana, Chuo-ku, Chiba 260-8675, Japan.
Abstract:
Phosphine-boryl radicals remain less well-studied because their parent phosphine-boranes are highly stable under oxidative conditions. Herein, we report a strategy for generating phosphine-boryl radicals facilitated by radical precursors through an appropriate molecular design. Incorporating a proximal oxidant into a phosphine-borane facilitates the formation of the corresponding boron-centered radical through proton-coupled intramolecular electron transfer. The resulting phosphine-boryl radical can be used to generate an alkyl radical via halogen atom transfer.
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