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Indirect Pulp Treatment for Deep Carious Lesions in Mature Permanent Teeth: A Preventive, Minimally Invasive Clinical
Liana Beresescu1, Alexandra Mihaela Stoica1, Csinszka Andrea Kovacs-Ivacson1
1Faculty of Dental Medicine, University of Medicine and Pharmacy, Science, and Technology George Emil Palade, 540139 Târgu-Mureș, Romania.
Dentistry Journal
|April 27, 2026
Summary
Indirect pulp treatment (IPT) using Biodentine or resin-modified glass ionomer cement (RMGIC) showed similar 12-month outcomes in adults. Both materials effectively preserved pulp vitality in deep carious lesions.
Area of Science:
- Dentistry
- Conservative Dentistry
- Dental Materials
Background:
- Indirect pulp treatment (IPT) is a conservative dental procedure to maintain pulp vitality in teeth with deep carious lesions.
- Limited evidence exists comparing liner materials for IPT in adult patients.
Purpose of the Study:
- To evaluate the 12-month clinical and radiographic outcomes of IPT using Biodentine versus resin-modified glass ionomer cement (RMGIC) in mature permanent teeth.
- To compare pulp vitality, postoperative pain, and radiographic changes between Biodentine and RMGIC in IPT.
Main Methods:
- A split-mouth clinical study involving adult patients with deep carious lesions in vital permanent teeth.
- Selective caries removal followed by IPT with either Biodentine or RMGIC.
- Clinical and radiographic assessments at baseline and 12 months.
Main Results:
- Pulp vitality was maintained in over 90% of teeth in both groups at 12 months, with no significant difference.
- Biodentine showed reduced postoperative pain at 24 hours compared to RMGIC, with differences resolving within a week.
- Comparable radiographic outcomes and a low incidence of periapical changes were observed for both materials.
Conclusions:
- Indirect pulp treatment with Biodentine or RMGIC yields similar 12-month clinical and radiographic results in mature permanent teeth.
- Pulp vitality preservation is achievable with different liner materials when employing minimally invasive techniques and effective coronal sealing.
- Further long-term follow-up is necessary to determine the durability of these treatments.
