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Updated: Apr 28, 2026

Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing
Published on: October 20, 2021
Quality of ChatGPT-Generated Responses to Common Patient Questions About Peripheral Nerve Stimulation: A
Charles A Odonkor1,2, Muhammad Uzair Siddique1, Sarvesh Palaniappan3
1Department of Orthopaedics and Rehabilitation, Division of Physiatry, Yale New Haven Hospital, 20 York Street, New Haven, CT 06510, USA.
ChatGPT-5.0 provides reliable and understandable information for patients undergoing peripheral nerve stimulation (PNS). While generally accurate for foundational and postoperative care, procedural details require clinician verification.
Area of Science:
- Neurology
- Pain Management
- Artificial Intelligence in Healthcare
Background:
- Peripheral nerve stimulation (PNS) is a growing treatment for neuropathic pain.
- Patients frequently seek online information regarding PNS procedures and recovery.
- Large language models (LLMs) like ChatGPT offer potential for scalable patient education.
Purpose of the Study:
- To evaluate the reliability, accuracy, and comprehensibility of ChatGPT-5.0 responses to common patient questions about PNS.
- To assess the performance of an LLM in providing patient education for a specific interventional pain procedure.
Main Methods:
- A cross-sectional study involving 21 standardized PNS-related questions.
- Expert consensus was used to formulate questions covering pre-implantation, implantation, and post-implantation phases.
- Board-certified interventional pain specialists and a nurse educator rated responses using validated scales for reliability, accuracy, and comprehensibility.
Main Results:
- ChatGPT-5.0 responses received generally high ratings for reliability (mean 4.7/6), accuracy (mean 2.6/3), and comprehensibility (mean 2.8/3).
- Questions about PNS mechanisms, expectations, and postoperative care were rated highest.
- Responses to implantation-specific questions requiring procedural nuance showed more variability.
Conclusions:
- ChatGPT-5.0 demonstrates capability in generating generally reliable, accurate, and understandable patient information for PNS, especially for non-procedural aspects.
- Clinician oversight is crucial for verifying information related to the procedural nuances of PNS implantation.
- This study establishes a benchmark for LLM performance in patient education for interventional pain management, highlighting the need for continuous evaluation.
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