Effects of a Greek Yoghurt-based Complex on the Human Facial Skin Microbiome

Area of Science:

• Dermo-cosmetics
• Microbiome research
• Dermatology

Background:

• Natural ingredient complexes are utilized in dermo-cosmetics for facial improvements.
• Limited human trials exist to demonstrate the efficacy of these natural complexes.
• This study investigates a Greek yogurt-based complex's impact on facial skin microbiome.

Purpose of the Study:

• To assess the effects of a Greek yogurt-based complex on the human facial skin microbiome.
• To compare the skin microbiome of individuals with stressed versus balanced facial skin.
• To evaluate changes in microbial diversity and composition following treatment.

Main Methods:

• A 28-day clinical study involving 31 volunteers with stressed skin and 15 with balanced skin.
• Skin swabs collected at baseline and on days 7, 14, and 28.
• 16S rRNA gene amplicon sequencing and bioinformatic analyses to assess microbial composition, diversity, and relative abundance.

Main Results:

• Lower microbiota diversity was observed in stressed facial skin compared to balanced skin at baseline.
• The four most abundant genera were Corynebacterium, Propionibacterium, Staphylococcus, and Actinomyces.
• A consistent increase in mean bacterial diversity was observed after intervention with the yogurt-based complex.

Conclusions:

• The Greek yogurt-based complex demonstrated a gradual restoration of the skin's microbial balance.
• This restoration is essential for healthy skin function and appearance.
• The findings support the use of natural ingredient complexes in dermo-cosmetics.